Nosotrack

Outbreak forensics for infection prevention and control.

NOSOTRACK™
Track.Intervene.Protect
Dr Cyril GeismarResearch Associate in Infectious Disease Data Analysis and ModellingImperial College LondonJohns Hopkins University

Infectious diseases are on the rise.

Infectious disease outbreaks pose a growing challenge to global health security.

Global connectivity, climate change, intensive farming, gaps in vaccination and antimicrobial resistance are accelerating the emergence and spread of infectious threats.

The WHO aims to detect and understand emerging health threats within 24 hours by 2030.

Understanding transmission is critical to outbreak control.

Every outbreak is different.

Effective control requires rapidly understanding where and how transmission occurred, identifying the index cases, superspreaders, undetected infections, importations; and determining who is most at risk.

Yet outbreak investigations remain manual, fragmented and time-consuming.

Nosotrack identifies the drivers of disease spread and guides targeted interventions.

The platform integrates clinical, genomic, contact and location data to infer likely transmission chains (who infected whom) in near real time, identify key drivers of transmission and optimise targeted interventions within operational constraints.

Healthcare is Nosotrack's initial market.

Healthcare-associated infections cost the NHS an estimated £2.7 billion annually, and individual hospital outbreaks can cost more than £1 million to control. They endanger vulnerable patients, disrupt hospital operations and consume substantial clinical resources.

Hospitals already collect much of the information needed to investigate outbreaks, but it remains fragmented across clinical records, microbiology and operational databases, leaving infection-prevention teams dependent on manual investigations.

From forensics to proactive control.

Nosotrack brings transmission intelligence into operational workflows, complementing existing infection-control systems with a unified view of how infections spread. This enables more targeted testing, isolation, contact tracing and environmental investigations.

A growing market for data-driven infection prevention and control.

Hospitals already invest in infection surveillance software, yet identifying transmission routes and selecting effective interventions still require substantial expert investigation.

Nosotrack goes beyond surveillance, providing model-based transmission attribution to inform targeted outbreak control.

Its commercial value lies in accelerating investigations, reducing secondary infections and optimising interventions within operational and resource constraints.

Peer-reviewed science, applied globally.

Built on over a decade of peer-reviewed research by our team and collaborators. Its inference engine (outbreaker2) builds on scientifically validated methods used to investigate outbreaks across pathogens, settings and countries.

Nosotrack is now translating this research into an operational platform. Currently in development, the platform is being extended with capabilities to identify contaminated sources (such as medical devices) and simulate interventions to optimise outbreak control.

From validated science to first hospital deployment.

The next step is to integrate Nosotrack into hospital surveillance systems and demonstrate its impact on outbreak control.

Hospital evaluations will assess whether Nosotrack can help teams identify and contain outbreaks faster, prevent secondary infections and reduce associated costs.

Funding will support secure data integration, product refinement and initial hospital pilots, establishing the evidence base for wider adoption.

Masked doctor marking progress through the collaboration

Audit

Understand existing practices, data and needs.

Validate

Evaluate Nosotrack using synthetic and historical outbreak data.

Pilot

Integrate Nosotrack into hospital surveillance workflows and evaluate its operational impact.

Pathogen agnostic, deployable anywhere.

Nosotrack aims to become the operating system for outbreak response, enabling organisations to investigate and control biological threats across settings and scales: from COVID-19 in care homes and norovirus on cruise ships to livestock infections on industrial farms, contamination in food supply chains and national biosecurity incidents.